The weekend is here again, and for punters, it is an opportunity to stake on matches across different leagues around the world. As we near the final stretch of the 2025/26 football season in Europe, punters need to know more details about the matches they want to bet on.

Teams now play to qualify for next season’s European competitions, avoid relegation, and win titles. We will take a look at some matches you can avoid each week, depending on club form, priority, and circumstances, to help punters reduce the risk of upsets on their betting slips.

Possible Upsets This Weekend

PSV – NEC Nijmegen

PSV hold a 19-point lead at the top of the Eredivisie table. The Dutch giants have all but secured qualification for next season’s UCL group phase, but the second UCL spot is still very much up for grabs.

NEC Nijmegen eliminated PSV from the Dutch Cup 10 days ago, but PSV’s desire for revenge might not burn as strongly as NEC Nijmegen’s desire to qualify for the Champions League for the first time in their history.

Opinion – There should be goals, but the game could swing either way regardless of what the odds say.

West Ham v Manchester City

This fixture is dicey, and that explains why, despite their stark contrast on the table, bookies have given West Ham a respectable 4.75 odds to pull off a win against City. Why?

Guardiola will rarely give up on a UCL tie after going 3-0 down in Madrid in midweek. Guardiola may rest some of his stars away against West Ham, and that could play into the hands of a team looking to leave the relegation zone.

Opinion – Unders could be a safe route for this tie, as West Ham do not score much and City might rotate.

Galatasaray – Istanbul Basaksehir

Galatasaray lead their two-legged tie against Liverpool. They will most likely rest players so they can stay fully fit to pull off a draw or win at Anfield. They are also playing against a top-five side in Turkey, so this match will be tough.

Opinion – If you must trust Galatasaray, insure the pick.

Barcelona v Sevilla

Barcelona are also in the middle of an important UCL tie against Newcastle United. The Blaugranas should beat an out-of-form Sevilla, but if the first meeting between these two sides offers any clue, you should approach this tie carefully as Barca might rest some tired legs.

Opinion – Barcelona will try to manage this game, but Sevilla should still score.

Sparta Prague – FC Slovacko

Sparta are overwhelming favourites to win this tie, but that could change if Sparta decide to rest players for their upcoming Conference League second-leg match against Dutch side Alkmaar after losing 2-1 in the first leg.

Opinion – Bets on goals might be better than a straight win here.

Midtjylland – Nordsjaelland

This tie normally produces goals in Denmark. These are two of the biggest sides in the league. However, Midtjylland have an all-important home game against Nottingham Forest coming up.

The Danish side already hold a one-goal lead against their English opponents, and they will look to rest players to ensure their best legs are ready to face Forest in the second leg.

Opinion – Midtjylland are favourites to win, but a 1X option might be wiser to cover a possible drop in quality.

Disclaimer – This is not 100% certain. These are just predictions based on context, fatigue, squad, form, and opponents. Anything can happen in a football game.